Found 147 articles for: "actinic keratosis"
Imiquimod 2.5% and 3.75% for the Treatment of Actinic Keratoses: Two Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled Studies
November 2013 | Volume 12 | Issue 11 | Original Article | 1278 | Copyright © November 2013
BACKGROUND: Imiquimod 3.75% and 2.5% creams were studied for the treatment of actinic keratosis (AK) of the full face or balding scalp, to determine comparable efficacy and tolerability to imiquimod ...
Read MoreThe Microsponge Delivery System Reduces Facial Oiliness and Shine During Acne Therapy
November 2013 | Volume 12 | Issue 11 | Original Article | 1268 | Copyright © November 2013
Acne therapies that are able to show efficacious treatment of acne lesions as well as to address the issues of oiliness and shine control may be particularly appropriate for the treatment of patients...
Read MoreGuest Editorial: Combination of Light and Energy-Based Technologies With Topical Drug Delivery
November 2013 | Volume 12 | Issue 11 | Editorials | 1208 | Copyright © November 2013
Valrubicin Activates PKCα in Keratinocytes: A Conceivable Mode of Action in Treating Hyper-Proliferative Skin Diseases
October 2013 | Volume 12 | Issue 10 | Original Article | 1156 | Copyright © October 2013
BACKGROUND: Valrubicin is a semisynthetic anthracycline developed as an anti-cancer drug able to ameliorate psoriasis and non-melanoma skin cancer (NMSC) by topical application in animal models. Valru...
Read MoreResident Spotlight. Orlando Dermatology Aesthetic & Clinical Conference (ODAC): Fourth Annual ARTE Poster Competition
August 2013 | Volume 12 | Issue 8 | Features | 949 | Copyright © August 2013
Current Methods for Photodynamic Therapy in the US: Comparison of MAL/PDT and ALA/PDT
August 2013 | Volume 12 | Issue 8 | Original Article | 925 | Copyright © August 2013
There is some debate regarding the rate of progression of actinic keratosis (AK) into squamous cell carcinoma (SCC).1-4 However, it is clear that treatment for AK lesions is warranted. Results from nu...
Read MoreA Review and Update on Melanocyte Stimulating Hormone Therapy: Afamelanotide
July 2013 | Volume 12 | Issue 7 | Original Article | 775 | Copyright © July 2013
Afamelanotide ([Nle4-D-Phe7]-alpha-MSH) is an analog of alpha-melanocyte stimulating hormone given as a subcutaneous injection. Afamelanotide is currently undergoing phase II and III trials in Europe ...
Read MoreThe History of Aesthetic Medicine and Surgery
July 2013 | Volume 12 | Issue 7 | Original Article | 737 | Copyright © July 2013
The history of beauty is as old as mankind itself - throughout history people have tried to improve their attractiveness and to enhance their beauty. The technical basis for many of nowadays procedure...
Read More40 Years of Topical Tretinoin Use in Review
June 2013 | Volume 12 | Issue 6 | Original Article | 638 | Copyright © June 2013
Topical tretinoin has been approved for use in dermatology for 40 years and is currently approved for the treatm...
Read MoreCosmeceuticals for Recurrence Prevention After Prior Skin Cancer: An Overview
May 2013 | Volume 12 | Issue 5 | Original Article | 516 | Copyright © May 2013
INTRODUCTION: Skin cancer is the most common form of cancer in the United States. According to the World Health Organization, the incidence of both nonmelanoma and melanoma skin cancers has increased ...
Read MoreMolecular Skin Research Can Impact Systemic Cancers
May 2013 | Volume 12 | Issue 5 | Editorials | 510 | Copyright © May 2013
Novel Use of Topical Dapsone 5% Gel for Erythema Elevatum Diutinum: Safer and Effective
April 2013 | Volume 12 | Issue 4 | Case Reports | 481 | Copyright © April 2013
We present a case of an otherwise healthy 81-year-old gentleman with multiple asymptomatic, erythematous, indurated papules and plaques, ranging in size from 0.5 to 1.5 cm, involving the dorsal, later...
Read MoreVitamin A and Its Derivatives in Experimental Photocarcinogenesis: Preventive Effects and Relevance to Humans
April 2013 | Volume 12 | Issue 4 | Original Article | 458 | Copyright © April 2013
The 1925 classical observation that vitamin A deficiency leads to squamous metaplasia and epithelial keratinization, coupled with the later finding that excess vitamin A inhibits keratinization of chi...
Read MoreKeloids: An Update on Medical and Surgical Treatments
April 2013 | Volume 12 | Issue 4 | Original Article | 403 | Copyright © April 2013
Keloids are the result of an overgrowth of dense fibrous tissue that usually develops after healing of a skin injury. Despite their common occurrence, keloids remain one of the most challenging dermat...
Read MoreTopical Formulation Engendered Alteration in p53 and Cyclobutane Pyrimidine Dimer Expression in Chronic Photodamaged Patients
March 2013 | Volume 12 | Issue 3 | Original Article | 336 | Copyright © March 2013
While the clinical attributes of photoaging are well characterized in the literature, the pathogenic mechanisms that underlie these changes are incompletely elucidated. At the molecular level, p53 tum...
Read MoreEfficacy of Topical 4% Quassia amara Gel in Facial Seborrheic Dermatitis:A Randomized, Double-Blind, Comparative Study
March 2013 | Volume 12 | Issue 3 | Original Article | 312 | Copyright © March 2013
BACKGROUND: Seborrheic dermatitis (SD) is a chronic mild skin disorder with high prevalence. Various treatment options are available, including topical antifungals and anti-inflammatories. Antifungal ...
Read MoreA Multicenter, Randomized, Vehicle-Controlled Phase 2 Study of Blue Light Photodynamic Therapy With Aminolevulinic Acid HCl 20% Topical Solution for the Treatment of Actinic Keratoses on the Upper Extremities: The Effect of Occlusion During the Drug Incubation Period
December 2012 | Volume 11 | Issue 12 | Original Article | 1483 | Copyright © December 2012
Background: Photodynamic therapy (PDT) with aminolevulinic acid (ALA) has been shown to be safe and effective in the treatment of actinic keratoses (AKs) of the face and scalp. A rec...
Read MoreThe Paradigm Shift in Treating Actinic Keratosis: A Comprehensive Strategy
December 2012 | Volume 11 | Issue 12 | Original Article | 1462 | Copyright © December 2012
Actinic keratoses (AKs) are cutaneous areas of atypical squamous transformation that are considered to be an early step in the continuum of transformation from normal skin to invasive and metastatic c...
Read MoreFractional Laser Skin Resurfacing
November 2012 | Volume 11 | Issue 11 | Original Article | 1274 | Copyright © November 2012
Laser skin resurfacing (LSR) has evolved over the past 2 decades from traditional ablative to fractional nonablative and fractional ablative resurfacing. Traditional ablative LSR was highly effective...
Read MoreMelanoma-Detecting Technologiesand Standard of Care
November 2012 | Volume 11 | Issue 11 | Editorials | 1270 | Copyright © November 2012